Computational Chemist (PhD)


Up ]
Addex Pharma is a rapidly growing Swiss based biopharmaceutical company engaged in the discovery and development of novel therapeutic compounds for the treatment of unmet medical needs. Addex Pharma S.A. is based in Plan-les-Ouates-Geneva/Switzerland.

We are is seeking to recruit a

Computational Chemist PhD (m/f)

The successful candidate will implement and drive the Computational Chemistry strategy for drug discovery projects at all stages, in order to deliver the highest standards of medicinal chemistry for the company. He/She will contribute to the broader strategy of the Chemoinformatic Unit in the field of allosteric modulation. He/she will collaborate across all discovery groups (such as Medicinal Chemistry, HTS, in vitro pharmacology, Metabolism and Pharmacokinetics (DMPK).

Qualified candidates will have a PhD in computational chemistry or molecular modeling with 2- 5 years Postdoctoral experience in computational chemistry within the pharmaceutical industry. He/she should have in-depth knowledge and expertise in more than one of the following areas: pharmacophore generation, small molecule modeling, 2D/3D QSAR, docking and scoring, virtual screening, de novo and ligand design methods, lead hopping, GPCR modeling and HTS analysis.

Demonstrated experience in applying modeling techniques to problems in the pharmaceutical industry, ranging from lead identification to optimization of compounds as preclinical candidates is essential.

A deep knowledge of fundamental molecular properties associated with all the steps of the life of a drug compound and of key molecular processes in pharmacodynamic and pharmacokinetic will also be requested.

Addex Pharma S.A. is seeking individuals with excellent communication skills who are creative, organized, enthusiastic, independent problem solver with excellent critical thinking skills and who able to work effectively in an international multidisciplinary discovery team environment.

To apply, send/e-mail your resume to:

Addex Pharma S.A.
Human resources
Chemin des Aulx 12
1228 Plan-les-Ouates, Switzerland
Addex-HR [at]

Please quote Comp Chem when replying.

Last updated: March 28, 2007

Comments to these pages to the site manager